XPO5 Antikörper (AA 221-320) (AbBy Fluor® 488)
-
- Target Alle XPO5 Antikörper anzeigen
- XPO5 (Exportin 5 (XPO5))
-
Bindungsspezifität
- AA 221-320
-
Reaktivität
- Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser XPO5 Antikörper ist konjugiert mit AbBy Fluor® 488
-
Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Exportin 5
- Isotyp
- IgG
- Top Product
- Discover our top product XPO5 Primärantikörper
-
anti-Exportin 5 (XPO5) (AA 1-280) antibody
XPO5 Reaktivität: Human WB, ELISA, IF, IP Wirt: Maus Monoclonal 2C5-1B3 unconjugated
anti-Exportin 5 (XPO5) (AA 925-1204) antibodyXPO5 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 1-1204) antibodyXPO5 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 1-1204) antibodyXPO5 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Exportin 5 (XPO5) antibodyXPO5 Reaktivität: Human, Maus, Ratte WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 1115-1164) antibodyXPO5 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Fledermaus, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 190-239) antibodyXPO5 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 182-231) antibodyXPO5 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 5 (XPO5) (N-Term) antibodyXPO5 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Exportin 5 (XPO5) (AA 2-180) antibodyXPO5 Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- XPO5 (Exportin 5 (XPO5))
- Andere Bezeichnung
- Exportin 5 (XPO5 Produkte)
- Hintergrund
-
Synonyms: Exp 5, Exp5, Exportin 5, Exportin-5, Exportin5, FLJ14239, FLJ32057, FLJ45606, KIAA1291, Ran binding protein 21, Ran-binding protein 21, Ranbp 21, Ranbp21, Xpo 5, xpo5, XPO5_HUMAN.
Background: Exportin 5 (XPO5) is a member of the importin _ family of proteins and functions in tRNA export in a sequence dependent fashion. More recently, it has been shown to export pre-miRNA by a RanGTPase-driven process from the nucleus to the cytoplasm, where pre-miRNA processing occurs to produce mature miRNAs. Study of the miRNA biosynthesis pathway is essential in understanding the process of oncogenesis as global downregulation of miRNAs and the resulting alterations in the expression of tumor suppressor and oncogenic proteins is a common phenotype of cancers cells . Research studies have shown disruption of exportin 5 functions in many types of cancers including breast and lung, where pre-miRNA accumulates in the nucleus and miRNA maturation is impaired.
- Pathways
- Regulatorische RNA Pathways, Protein targeting to Nucleus
-
