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ZBTB17 Antikörper (AA 331-430) (FITC)

ZBTB17 Reaktivität: Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN1390070
  • Target Alle ZBTB17 Antikörper anzeigen
    ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))
    Bindungsspezifität
    • 14
    • 14
    • 8
    • 1
    • 1
    AA 331-430
    Reaktivität
    • 24
    • 24
    • 9
    Maus
    Wirt
    • 39
    Kaninchen
    Klonalität
    • 39
    Polyklonal
    Konjugat
    • 9
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ZBTB17 Antikörper ist konjugiert mit FITC
    Applikation
    • 31
    • 16
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Miz1/ZNF60
    Isotyp
    IgG
    Top Product
    Discover our top product ZBTB17 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ZBTB17 (Zinc Finger and BTB Domain Containing 17 (ZBTB17))
    Andere Bezeichnung
    Miz1/ZNF60 (ZBTB17 Produkte)
    Synonyme
    MIZ-1 antikoerper, ZNF151 antikoerper, ZNF60 antikoerper, pHZ-67 antikoerper, AA589413 antikoerper, Lp-1 antikoerper, Miz1 antikoerper, Zfp100 antikoerper, mZ13 antikoerper, Miz-1 antikoerper, zbtb17 antikoerper, zinc finger and BTB domain containing 17 antikoerper, zinc finger and BTB domain containing 17 S homeolog antikoerper, ZBTB17 antikoerper, Zbtb17 antikoerper, zbtb17.S antikoerper
    Hintergrund

    Synonyms: Miz-1, Myc-interacting zinc finger protein 1, Myc-interacting zinc finger protein, ZBT17, ZBT17_HUMAN, Zbtb17, Zinc finger and BTB domain containing protein 17, Zinc finger and BTB domain-containing protein 17, Zinc finger protein 151, Zinc finger protein 60, ZNF151, ZNF60.

    Background: The Myc family, including c-Myc-, N-Myc- and L-Myc, are nuclear proteins with relatively short half lives that contribute an important role in cellular processes such as proliferation, differentiation, apoptosis and transformation. The c-Myc protein activates transcription as part of a heteromeric complex with a number of interacting partners, including Max and Mxi 1, however the transforming properties of the Myc proto-oncogene are believed to be associated with Myc-mediated transcriptional repression. A POZ domain Zn finger protein, designated Miz-1 for Myc-interacting Zn finger protein-1, is a specific target of Myc-induced gene repression. Miz-1 interacts with Myc, but not Max or other Myc partners, and binding of Myc to Miz-1 requires the helix-loop-helix domain of Myc and a short amphipathic helix located in the carboxy-terminus of Miz-1. Miz-1 associates with DNA elements on the adenovirus major late and cyclin D1 promoters and activates transcription of both promoters. Expression of Miz-1 induces potent growth arrest function, and this latency is reversed by the addition of Myc.

    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, ER-Nucleus Signaling
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