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CREB3L3 Antikörper (AA 201-300) (Biotin)

CREB3L3 Reaktivität: Human WB, ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1390099
  • Target Alle CREB3L3 Antikörper anzeigen
    CREB3L3 (cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3))
    Bindungsspezifität
    • 15
    • 1
    • 1
    • 1
    AA 201-300
    Reaktivität
    • 25
    • 8
    • 8
    Human
    Wirt
    • 25
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CREB3L3 Antikörper ist konjugiert mit Biotin
    Applikation
    • 18
    • 14
    • 13
    • 13
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CREB-H
    Isotyp
    IgG
    Top Product
    Discover our top product CREB3L3 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    CREB3L3 (cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3))
    Andere Bezeichnung
    CREB-H/CREB3L3 (CREB3L3 Produkte)
    Synonyme
    CREB-H antikoerper, CREBH antikoerper, BC010786 antikoerper, D10Bur1e antikoerper, creb3l3a antikoerper, creb3l3b antikoerper, si:dkey-110c1.2 antikoerper, wu:fc88h05 antikoerper, zgc:112279 antikoerper, cAMP responsive element binding protein 3 like 3 antikoerper, cAMP responsive element binding protein 3-like 3 antikoerper, cAMP responsive element binding protein 3-like 3a antikoerper, CREB3L3 antikoerper, Creb3l3 antikoerper, creb3l3a antikoerper
    Hintergrund

    Synonyms: cAMP responsive element binding protein 3 like 3, cAMP responsive element-binding protein 3 like protein 3, CREB H, CREB/ATF family transcription factor, CREBH, Cyclic AMP responsive element binding protein 3 like protein 3, cAMP-responsive element-binding protein 3-like protein 3, HYST1481, MGC126553, MGC126557, Transcription factor CREB H, CR3L3_HUMAN.

    Background: CREB3L3 is a 461 amino acid single-pass type II membrane protein that localizes to the endoplasmic reticulum (ER) and, in response to ER stress, is cleaved and translocated to the nucleus. Expressed exclusively in liver, CREB3L3 functions as a transcription factor that, during ER stress, is thought to activate genes that are involved in both the unfolded protein response and the acute phase response (APR). Additionally, CREB3L3 is underexpressed in hepatocellular carcinoma, suggesting a possible role as a tumor suppressor. CREB3L3 functions as a dimer and contains one leucine zipper domain, a KDEL-like sequence and a bZIP domain, through which it conveys its DNA binding ability. Three isoforms of CREB3L3 exist due to alternative splicing events.

    Pathways
    Thyroid Hormone Synthesis
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