Endothelin 2 Antikörper (AA 49-59) (AbBy Fluor® 555)
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- Target Alle Endothelin 2 (EDN2) Antikörper anzeigen
- Endothelin 2 (EDN2)
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Bindungsspezifität
- AA 49-59
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Reaktivität
- Cat
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Endothelin 2 Antikörper ist konjugiert mit AbBy Fluor® 555
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Cat
- Homologie
- Human,Mouse,Rat,Dog,Cow,Cat,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Endolin 2
- Isotyp
- IgG
- Top Product
- Discover our top product EDN2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Endothelin 2 (EDN2)
- Andere Bezeichnung
- ET-2/Endothelin 2 (EDN2 Produkte)
- Synonyme
- endothelin-2 antikoerper, EDN2 antikoerper, si:ch211-202b2.2 antikoerper, ET2 antikoerper, PPET2 antikoerper, VIC antikoerper, Et2 antikoerper, ET-2 antikoerper, endothelin 2 antikoerper, EDN2 antikoerper, edn2 antikoerper, Edn2 antikoerper
- Hintergrund
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Synonyms: EDN2, EDN2_HUMAN, Endothelin 2, Endothelin-2, ET 2, ET-2, ET2, PPET2, Preproendothelin 2, Preproendothelin-2.
Background: The endothelin (ET) family of proteins, which includes ET-1 (endothelin-1), ET-2 (endothelin-2) and ET-3 (endothelin-3), are vasoactive peptides that are involved in various functions throughout the body. Endothelins can affect the central nervous system and neuronal excitability, and they elicit potent vasoconstrictor action. While ET-1 is a potent, 21-amino acid vasoconstrictor peptide, ET-2 has the most potent vasoconstrictor activity. ET-3 functions as a ligand for endothelin receptor type B (ETBR) and, through this interaction, mediates the maturation of enteric neurons and melanocytes. Although ET-3 is expressed as a 238 amino acid peptide, it is post-translationally modified to produce a short active isoform and a long inactive isoform. Defects in the gene encoding ET-3 are the cause of a variety of disorders, including Hirschsprung disease type 1 (HSCR1), congenital central hypoventilation syndrome (CCHS) and Waardenburg syndrome type IV (WS4).
- Pathways
- Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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