NAB2 Antikörper (AbBy Fluor® 488)
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- Target Alle NAB2 Antikörper anzeigen
- NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NAB2 Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NAB2
- Isotyp
- IgG
- Top Product
- Discover our top product NAB2 Primärantikörper
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))
- Andere Bezeichnung
- Nab2/Mader (NAB2 Produkte)
- Synonyme
- mader antikoerper, AI451907 antikoerper, MADER antikoerper, NGFI-A binding protein 2 (EGR1 binding protein 2) antikoerper, Ngfi-A binding protein 2 antikoerper, NGFI-A binding protein 2 antikoerper, nab2 antikoerper, Nab2 antikoerper, NAB2 antikoerper
- Hintergrund
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Synonyms: EGR 1 binding protein 2, EGR-1-binding protein 2, EGR1 binding protein 2, MADER, Melanoma associated delayed early response protein, Melanoma-associated delayed early response protein, MGC75085, Nab 2, nab2, NAB2_HUMAN, NGFI A binding protein 2 EGR1 binding protein 2, NGFI A binding protein 2, NGFI-A-binding protein 2, Protein MADER.
Background: Transcriptional control is in part regulated by interactions between DNA-bound transcription factors, such as Egr-1/NGFI-A, and coregulatory proteins, such as NAB (for NGFI-A-binding proteins). The evolutionarily conserved NAB proteins, NAB1 and NAB2 are corepressors of EGF-1/NGFI-A. Both NAB1 and NAB2 contain an amino terminal NAB conserved domain 1 (NCB1), which is required for binding NGFI-A, and a carboxy terminal NCD2 domain, which is responsible for the repressor function of NAB proteins. NAB2 is principally localized in the nucleus and may play a role in the downregulation of NGFI-A activity as well as in controlling fundamental processes such as cell division, differentiation and apoptosis. NAB2 localizes to chromosome 12q13.3-14.1, a region that is rearranged in several solid tumors, lipomas, and liposarcomas.
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