SV2B Antikörper (AA 401-500) (AbBy Fluor® 555)

Produktnummer ABIN1390841

Produktdetails anti-SV2B Antikörper (AbBy Fluor® 555)

Target: SV2B (Synaptic Vesicle Glycoprotein 2B (SV2B))

Bindungsspezifität: AA 401-500

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SV2B Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SV2B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SV2B

Target: SV2B (Synaptic Vesicle Glycoprotein 2B (SV2B))

Andere Bezeichnung: SV2B (SV2B Produkte)

Synonyme: SV2B antikoerper, A830038F04Rik antikoerper, AI850768 antikoerper, mKIAA0735 antikoerper, HsT19680 antikoerper, synaptic vesicle glycoprotein 2B antikoerper, synaptic vesicle glycoprotein 2 b antikoerper, synaptic vesicle glycoprotein 2b antikoerper, SV2B antikoerper, CpipJ_CPIJ009611 antikoerper, Sv2b antikoerper

Hintergrund:

Synonyms: Synaptic vesicle protein 2B, SV2B_HUMAN.

Background: In all vertebrates, SV2 proteins are abundant, hydrophobic, membrane glycoproteins that are expressed as two major isoforms, SV2A and SV2B, and one minor isoform, SV2C. SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, independent of transmitter type. SV2A is abundantly expressed in the subcortex, specifically in the synaptic vesicles of all presynaptic nerve terminals, and also in most neuroendocrine secretory granules. SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex. SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates. SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation.

Gen-ID: 9899