SV2C Antikörper (AA 451-550) (Biotin)

Produktnummer ABIN1390849

Produktdetails anti-SV2C Antikörper (Biotin)

Target: SV2C (Synaptic Vesicle Glycoprotein 2C (SV2C))

Bindungsspezifität: AA 451-550

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SV2C Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SV2C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SV2C

Target: SV2C (Synaptic Vesicle Glycoprotein 2C (SV2C))

Andere Bezeichnung: SV2C (SV2C Produkte)

Synonyme: si:dkey-18p14.1 antikoerper, 4930527L09Rik antikoerper, AI841971 antikoerper, synaptic vesicle glycoprotein 2C antikoerper, synaptic vesicle glycoprotein 2c antikoerper, SV2C antikoerper, sv2c antikoerper, CpipJ_CPIJ005417 antikoerper, Sv2c antikoerper

Hintergrund:

Synonyms: Synaptic vesicle protein 2c, SV2C_HUMAN.

Background: In all vertebrates, SV2 proteins are abundant, hydrophobic, membrane glycoproteins that are expressed as two major isoforms, SV2A and SV2B, and one minor isoform, SV2C. SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, independent of transmitter type. SV2A is abundantly expressed in the subcortex, specifically in the synaptic vesicles of all presynaptic nerve terminals, and also in most neuroendocrine secretory granules. SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex. SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates. SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation.

Gen-ID: 22987