Synaptojanin 1 Antikörper (AA 481-580) (Biotin)

Produktnummer ABIN1390909

Produktdetails anti-Synaptojanin 1 Antikörper (Biotin)

Target: Synaptojanin 1 (SYNJ1)

Bindungsspezifität: AA 481-580

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Synaptojanin 1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Synaptojanin/INPP5G

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Synaptojanin 1

Target: Synaptojanin 1 (SYNJ1)

Andere Bezeichnung: Synaptojanin 1 (SYNJ1 Produkte)

Synonyme: CG6562 antikoerper, Dmel\\CG6562 antikoerper, IPP antikoerper, Synj antikoerper, fb02f11 antikoerper, fi15a11 antikoerper, nrc antikoerper, wu:fb02f11 antikoerper, wu:fi15a11 antikoerper, SYNJ1 antikoerper, INPP5G antikoerper, A930006D20Rik antikoerper, AA675315 antikoerper, mKIAA0910 antikoerper, Synaptojanin antikoerper, synaptojanin 1 antikoerper, Synj antikoerper, synj1 antikoerper, SYNJ1 antikoerper, Synj1 antikoerper

Hintergrund:

Synonyms: 5-trisphosphate 5-phosphatase 1, Inositol 5' phosphatase, INPP 5G, INPP5G, KIAA0910, Polyphosphoinositide phosphatase, Synaptic inositol 1 4 5 trisphosphate 5 phosphatase 1, Synaptic inositol 145 trisphosphate 5 phosphatase 1, Synaptic inositol-1 antibody Synaptic inositol-145-trisphosphate 5-phosphatase 1, Synaptojanin 1, Synaptojanin 1 polyphosphoinositide phosphatase, Synaptojanin-1, Synaptojanin1, Synj 1, Synj1, SYNJ1_HUMAN.

Background: The inositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of various phosphatidylinositols, which generate second messengers in response to extracellular signals. Synaptojanins are characterized by an N-terminal SAC1-like sequence, a central 5-phosphate domain, and a unique C-terminal sequence and have been shown to use phosphatidylinositol 4,5-bisphosphate as a substrate. Synaptojanins exist as two isoforms, synaptojanin 1 and 2, which differ in the C-terminal domain, and each isoform has multiple variants produced by alternative splicing. Synaptojanin 1 is expressed as two major forms: the shorter is found in brain while the longer is expressed in peripheral tissues. Eight splice variants of synaptojanin 2 have been detected, including a brain specific isoform. Synaptojanins are thought to participate in the endocytosis of synaptic vesicles and the regulation of the actin cytoskeleton.

Gen-ID: 8867

Pathways: Inositol Metabolic Process, Synaptic Vesicle Exocytosis