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AACS Antikörper (AA 182-228) (AbBy Fluor® 350)

AACS Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 350
Produktnummer ABIN1390947
  • Target Alle AACS Antikörper anzeigen
    AACS (Acetoacetyl-CoA Synthetase (AACS))
    Bindungsspezifität
    • 14
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 182-228
    Reaktivität
    • 33
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 32
    • 1
    Kaninchen
    Klonalität
    • 33
    Polyklonal
    Konjugat
    • 14
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AACS Antikörper ist konjugiert mit AbBy Fluor® 350
    Applikation
    • 27
    • 13
    • 12
    • 12
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human AACS
    Isotyp
    IgG
    Top Product
    Discover our top product AACS Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    AACS (Acetoacetyl-CoA Synthetase (AACS))
    Andere Bezeichnung
    AACS/ACSF1 (AACS Produkte)
    Synonyme
    sur-5 antikoerper, An08g04090 antikoerper, AO090001000376 antikoerper, ACSF1 antikoerper, SUR-5 antikoerper, 2210408B16Rik antikoerper, SUR5 antikoerper, zgc:56105 antikoerper, acetoacetyl-CoA synthetase antikoerper, bll4282 antikoerper, acetoacetyl-coa synthetase antikoerper, acetoacetate--CoA ligase antikoerper, acetoacetate-CoA ligase antikoerper, Acetoacetyl-CoA synthetase antikoerper, AACS antikoerper, LOC590598 antikoerper, aacs antikoerper, bll4282 antikoerper, Pfl01_3080 antikoerper, h16_A2860 antikoerper, Mflv_1473 antikoerper, ANI_1_594074 antikoerper, Pput_2653 antikoerper, VIBHAR_RS20435 antikoerper, AOR_1_648164 antikoerper, CC1G_04522 antikoerper, LACBIDRAFT_230952 antikoerper, PLES_33261 antikoerper, PA1997 antikoerper, OB0504 antikoerper, CBU_0766 antikoerper, acsA2 antikoerper, Sde_0006 antikoerper, Plav_1154 antikoerper, AZC_2243 antikoerper, SGR_RS30655 antikoerper, Aacs antikoerper, sur-5 antikoerper
    Hintergrund

    Synonyms: Acetoacetyl-CoA synthetase, ACSF1, Acyl-CoA synthetase family member 1, Protein sur-5 homolog, AACS_HUMAN.

    Background: ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR?target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.

    Gen-ID
    65985
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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