AANAT Antikörper (pThr29) (Biotin)

Produktnummer ABIN1391335

Produktdetails anti-AANAT Antikörper (Biotin)

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Bindungsspezifität: pThr29

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AANAT Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Dog,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse AANAT around the phosphorylation site of Thr29

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu AANAT

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Andere Bezeichnung: Aanat (AANAT Produkte)

Synonyme: DSPS antikoerper, SNAT antikoerper, AA-NAT antikoerper, Nat4 antikoerper, Nat-2 antikoerper, Snat antikoerper, aralkylamine N-acetyltransferase antikoerper, arylalkylamine N-acetyltransferase antikoerper, AANAT antikoerper, Aanat antikoerper

Hintergrund:

Synonyms: p-AANATThr29, p-AANATT29, AANATphospho Thr29, p-AANATT29

Background: Arylalkylamine N-acetyltransferase belongs to the superfamily of acetyltransferases. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for seasonal reproduction, modulates the function of the circadian clock in the suprachiasmatic nucleus, and influences activity and sleep. This enzyme is rapidly inactivated when animals are exposed to light at night. This protein is 80 % identical to sheep and rat AA-NAT. Arylalkylamine N-acetyltransferase may contribute a multifactorial genetic diseases such as altered behavior in sleep/wake cycle.

Gen-ID: 11298

Pathways: Photoperiodism