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ABLIM1 Antikörper (AA 681-778) (Biotin)

ABLIM1 Reaktivität: Human WB, ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1391341
  • Target Alle ABLIM1 Antikörper anzeigen
    ABLIM1 (Actin Binding LIM Protein 1 (ABLIM1))
    Bindungsspezifität
    • 14
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 681-778
    Reaktivität
    • 41
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 37
    • 4
    Kaninchen
    Klonalität
    • 40
    • 1
    Polyklonal
    Konjugat
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ABLIM1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 27
    • 13
    • 13
    • 12
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Pig,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ABLIM1
    Isotyp
    IgG
    Top Product
    Discover our top product ABLIM1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    ABLIM1 (Actin Binding LIM Protein 1 (ABLIM1))
    Andere Bezeichnung
    ABLIM1 (ABLIM1 Produkte)
    Synonyme
    ABLIM1 antikoerper, 2210411C18Rik antikoerper, 2610209L21Rik antikoerper, 4833406P10Rik antikoerper, 9330196J19Rik antikoerper, AV079770 antikoerper, AW060987 antikoerper, AW215784 antikoerper, Limab1 antikoerper, abLIM-L antikoerper, abLIM-M antikoerper, abLIM-S antikoerper, mKIAA0059 antikoerper, ablim1 antikoerper, zgc:172321 antikoerper, RGD1565768 antikoerper, ABLIM antikoerper, LIMAB1 antikoerper, LIMATIN antikoerper, abLIM-1 antikoerper, si:dkeyp-84e12.1 antikoerper, zgc:112954 antikoerper, actin binding LIM protein 1 antikoerper, actin-binding LIM protein 1 antikoerper, actin binding LIM protein 1a antikoerper, actin binding LIM protein 1b antikoerper, ABLIM1 antikoerper, Ablim1 antikoerper, ablim1a antikoerper, ablim1b antikoerper
    Hintergrund

    Synonyms: ABLIM 1, ABLIM, abLIM-1, ABLIM-L, ABLIM-M, ABLIM-S, ABLIM1, ABLM1_HUMAN, Actin binding double zinc finger protein, Actin binding LIM protein 1, Actin binding LIM protein family member 1, Actin-binding double zinc finger protein, Actin-binding double zinc finger protein, Actin-binding LIM protein 1, Actin-binding LIM protein family member 1, DKFZp781D0148, FLJ14564, KIAA0059, LIM actin binding protein 1, LIMAB 1, LIMAB1, Limatin, RGD1565768, RP11-317F20.1.

    Background: The C. elegans protein Unc-115 mediates axon guidance by modulating the growth cone Actin cytoskeleton in response to signals received by growth cone receptors. The mammalian homolog of Unc-115 is the Actin-binding LIM protein family member 1 (ABLIM1, also designated Limatin). The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription.

    Gen-ID
    3983
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