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ATRNL1 Antikörper (AA 501-600) (AbBy Fluor® 488)

ATRNL1 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN1391656
  • Target Alle ATRNL1 Antikörper anzeigen
    ATRNL1 (Attractin-Like 1 (ATRNL1))
    Bindungsspezifität
    • 14
    • 1
    AA 501-600
    Reaktivität
    • 17
    • 2
    Human
    Wirt
    • 17
    Kaninchen
    Klonalität
    • 17
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ATRNL1 Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ATRNL1
    Isotyp
    IgG
    Top Product
    Discover our top product ATRNL1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ATRNL1 (Attractin-Like 1 (ATRNL1))
    Andere Bezeichnung
    ATRNL1 (ATRNL1 Produkte)
    Synonyme
    AI504415 antikoerper, AW555641 antikoerper, Alp antikoerper, Atrnl antikoerper, Atrnlp antikoerper, RGD1563485 antikoerper, ALP antikoerper, bA338L11.1 antikoerper, bA454H24.1 antikoerper, attractin like 1 antikoerper, ATRNL1 antikoerper, Atrnl1 antikoerper
    Hintergrund

    Synonyms: ATRN1_HUMAN, ATRNL1, Attractin-like protein 1, KIAA0534.

    Background: ATRNL1 is a 1,379 amino acid single-pass type I membrane protein that may play a role in melanocortin signaling pathways that regulate energy homeostasis. The ATRNL1 protein contains a C-type lectin domain, a CUB domain, two EGF-like domains, six Kelch repeats, two laminin EGF-like domains and five PSI domains. ATRNL1 interacts with MC4-R in several regions known to be important in the regulation of energy homeostasis by melanocortins, such as the paraventricular nucleus of hypothalamus and the dorsal motor nucleus of the vagus. The ATRNL1 gene is conserved in dog, cow, mouse, rat, chicken, zebrafish and C. elegans, exists as two alternatively spliced isoforms and maps to human chromosome 10q25.3. Strong evidence of linkage to late-onset Alzheimer disease (LOAD) is linked to chromosome 10, which implicates a wide region and at least one disease-susceptibility locus.

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