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BBS9 Antikörper (AA 244-320) (AbBy Fluor® 647)

BBS9 Reaktivität: Ratte IF (p), IF (cc) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN1391700
  • Target Alle BBS9 Antikörper anzeigen
    BBS9 (Bardet-Biedl Syndrome 9 (BBS9))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    AA 244-320
    Reaktivität
    • 30
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Ratte
    Wirt
    • 44
    Kaninchen
    Klonalität
    • 44
    Polyklonal
    Konjugat
    • 11
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BBS9 Antikörper ist konjugiert mit AbBy Fluor® 647
    Applikation
    • 20
    • 19
    • 12
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human BBS9
    Isotyp
    IgG
    Top Product
    Discover our top product BBS9 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    BBS9 (Bardet-Biedl Syndrome 9 (BBS9))
    Andere Bezeichnung
    BBS9 (BBS9 Produkte)
    Synonyme
    b1 antikoerper, B1 antikoerper, C18 antikoerper, D1 antikoerper, PTHB1 antikoerper, RGD1308472 antikoerper, E130103I17Rik antikoerper, Bardet-Biedl syndrome 9 antikoerper, bardet-biedl syndrome 9 antikoerper, Bardet-Biedl syndrome 9 (human) antikoerper, BBS9 antikoerper, bbs9 antikoerper, Bbs9 antikoerper
    Hintergrund

    Synonyms: B1, D1, C18, PTHB1, Protein PTHB1, Bardet-Biedl syndrome 9 protein, Parathyroid hormone-responsive B1 gene protein, BBS9

    Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.

    Gen-ID
    27241
    UniProt
    Q3SYG4
    Pathways
    Hedgehog Signalweg
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