FADS2 Antikörper (AbBy Fluor® 350)

Produktnummer ABIN1391727

Produktdetails anti-FADS2 Antikörper (AbBy Fluor® 350)

Target: FADS2 (Fatty Acid Desaturase 2 (FADS2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FADS2 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FADS2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FADS2

Target: FADS2 (Fatty Acid Desaturase 2 (FADS2))

Andere Bezeichnung: Fads2 (FADS2 Produkte)

Synonyme: D6D antikoerper, DES6 antikoerper, FADSD6 antikoerper, LLCDL2 antikoerper, SLL0262 antikoerper, TU13 antikoerper, FADS5 antikoerper, MSTP008 antikoerper, SCD1 antikoerper, SCDOS antikoerper, 2900042M13Rik antikoerper, Fadsd2 antikoerper, Fadsd6 antikoerper, DRD5/D6 antikoerper, wu:fb64c04 antikoerper, wu:fb69e08 antikoerper, zgc:112502 antikoerper, fatty acid desaturase 2 antikoerper, stearoyl-CoA desaturase antikoerper, fatty acid desaturase 2 L homeolog antikoerper, FADS2 antikoerper, SCD antikoerper, Fads2 antikoerper, fads2 antikoerper, fads2.L antikoerper

Hintergrund:

Synonyms: D6D, Delta6 desaturase, Delta6 fatty acid desaturase, DES 6, DES6, FADS 2, FADSD 6, FADSD6, Fatty acid desaturase 2, linoleoyl-CoA desaturase delta-6-desaturase like 2, LLCDL 2, LLCDL2, SLL0262, TU 13, TU13, FADS2_HUMAN.

Background: Members of the fatty acid desaturase (FADS) family, including FADS1, FADS2 and FADS3, regulate the desaturation of fatty acids by introducing double bonds between defined carbons of fatty acyl chains, thereby playing an essential role in the lipid metabolic pathway. Members of this family share N-terminal cytochrome b5-like domains, C-terminal multiple membrane-spanning desaturase regions and 3 histidine box motifs. FADS2 (fatty acid desaturase 2), also known as D6D, DES6, LLCDL2 or TU13, is a 444 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one cytochrome b5 heme-binding domain. Expressed in adult and fetal heart and in adult liver, brain, lung and retina, FADS2 functions as a component of a lipid metabolic pathway and catalyzes the first step in the pathway, namely the formation of unsaturated fatty acids from polyunsaturated fatty acids. Defects in the gene encoding FADS2 are the cause of cause of fatty acid delta-6-desaturase deficiency, an affliction that is characterized by skin abnormalities, corneal ulceration and growth failure. Multiple isoforms of FADS2 exist due to alternative splicing events.