Neuropeptide Antikörper (AA 91-133) (Biotin)

Produktnummer ABIN1391839

Produktdetails anti-Neuropeptide Antikörper (Biotin)

Target: Neuropeptide

Bindungsspezifität: AA 91-133

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuropeptide Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human QRFP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Neuropeptide

Target: Neuropeptide

Andere Bezeichnung: QRFP (Neuropeptide Produkte)

Synonyme: 26RFa antikoerper, P518 antikoerper, pyroglutamylated RFamide peptide antikoerper, QRFP antikoerper, Qrfp antikoerper

Hintergrund:

Synonyms: 26RFa, Neuropeptide RF-amide, OX26_HUMAN, pyroglutamylated RFamide peptide, P518, Pyroglutamylated arginine-phenylalanine-amide peptide, QRF-amide, Qrfp.

Background: QRFP is a 136 amino acid secreted protein that is widely expressed in the brain with highest expression levels in the cerebellum, medulla, pituitary, retina, vestibular nucleus and white matter. Also expressed in the bladder, colon, coronary artery, parathyroid gland, prostate, testis and thyroid, QRFP is a member of the RFamide neuropeptide family. QRFP may be involved in aldosterone secretion by the adrenal gland and is also implicated in stimulating metabolic rate, locomotor activity and increasing blood pressure. Considered a ligand for the G-protein coupled receptor GPR103, QRFP may have orexigenic activity, thereby acting as an appetite stimulant. The gene encoding QFRP is located on human chromosome 9, which consists of about 145 million bases, comprises roughly 4 % of the human genome and encodes nearly 900 genes.