Homeobox C5 Antikörper (AA 151-222) (AbBy Fluor® 647)
Kurzübersicht für Homeobox C5 Antikörper (AA 151-222) (AbBy Fluor® 647) (ABIN1392168)
Target
Alle Homeobox C5 (HOXC5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 151-222
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Kreuzreaktivität
- Human, Maus
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Homologie
- Rat,Dog,Cow,Sheep
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human HOXC5
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- Homeobox C5 (HOXC5)
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Andere Bezeichnung
- HOXC5
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Hintergrund
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Synonyms: CP11, homeo box C5, homeobox C5, Homeobox protein CP11, homeobox protein Hox C5, Homeobox protein Hox-3D, Homeobox protein Hox-C5, Hox 3D, HOX3, HOX3D, HOXC5, HXC5_HUMAN, OTTHUMP00000217386.
Background: The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxC5 is a 222 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Existing as multiple alternatively spliced isoforms, HoxC5 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. The gene encoding HoxC5 maps to a cluster of Hox proteins on chromosome 12 that are essential for morphogenesis. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia.
Target
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