NOMO1 Antikörper (AA 701-800) (AbBy Fluor® 488)

Produktnummer ABIN1392202

Produktdetails anti-NOMO1 Antikörper (AbBy Fluor® 488)

Target: NOMO1 (NODAL Modulator 1 (NOMO1))

Bindungsspezifität: AA 701-800

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOMO1 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NOMO1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NOMO1

Target: NOMO1 (NODAL Modulator 1 (NOMO1))

Andere Bezeichnung: NOMO1 (NOMO1 Produkte)

Synonyme: Nomo antikoerper, PM5 antikoerper, D7Ertd156e antikoerper, pM5 antikoerper, RGD1305240 antikoerper, NOMO2 antikoerper, DKFZP459L1733 antikoerper, Nomo1 antikoerper, NODAL modulator 1 antikoerper, nodal modulator 1 antikoerper, NOMO1 antikoerper, Nomo1 antikoerper, LOC515570 antikoerper, LOC714226 antikoerper, LOC100025365 antikoerper, LOC100174326 antikoerper, LOC100408200 antikoerper, LOC100464689 antikoerper, LOC100544619 antikoerper, LOC100626015 antikoerper, LOC454345 antikoerper, LOC489992 antikoerper, LOC100713781 antikoerper

Hintergrund:

Synonyms: Nodal modulator 1, NOMO 1, Nomo, NOMO1, NOMO1_HUMAN, PM5, pM5 protein, pM5 protein telomeric copy, NOMO1_HUMAN.

Background: Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).