SOX8 Antikörper (AA 101-200) (Biotin)

Produktnummer ABIN1392235

Produktdetails anti-SOX8 Antikörper (Biotin)

Target: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Bindungsspezifität: AA 101-200

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX8 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SOX8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SOX8

Target: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Andere Bezeichnung: SOX8 (SOX8 Produkte)

Synonyme: SRY-box 8 antikoerper, SRY box 8 antikoerper, SRY-box 8 L homeolog antikoerper, SRY (sex determining region Y)-box 8 antikoerper, SOX8 antikoerper, Sox8 antikoerper, sox8.L antikoerper

Hintergrund:

Synonyms: SOX 8, Sox8, SOX8_HUMAN, SRY sex determining region Y box 8, SRY box 8, SRY box containing gene 8, Transcription factor SOX 8, Transcription factor SOX-8, Transcription factor SOX8.

Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Pathways: Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development