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GSX1/GSH1 Antikörper (AA 165-264) (AbBy Fluor® 488)

GSX1 Reaktivität: Maus WB, IF (p), IF (cc) Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN1392304
  • Target Alle GSX1/GSH1 (GSX1) Antikörper anzeigen
    GSX1/GSH1 (GSX1) (GS Homeobox 1 (GSX1))
    Bindungsspezifität
    • 14
    • 5
    • 2
    AA 165-264
    Reaktivität
    • 17
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 23
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GSX1/GSH1 Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 18
    • 12
    • 12
    • 9
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Sheep,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Gsh1
    Isotyp
    IgG
    Top Product
    Discover our top product GSX1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    GSX1/GSH1 (GSX1) (GS Homeobox 1 (GSX1))
    Andere Bezeichnung
    Gsh1 (GSX1 Produkte)
    Synonyme
    gsh1 antikoerper, im:7138106 antikoerper, zgc:110817 antikoerper, GSH1 antikoerper, gsh-1 antikoerper, Gsh-1 antikoerper, Gsh1 antikoerper, GS homeobox 1 antikoerper, gsx1 antikoerper, GSX1 antikoerper, Gsx1 antikoerper
    Hintergrund

    Synonyms: GS homeo box protein 1, GS homeobox 1, GSH1, GSX1, GSX1_HUMAN, Homeobox protein GSH-1 , Homeobox protein Gsh1.

    Background: Growth hormone-releasing hormone (GHRH) stimulates secretion and synthesis of growth hormone (GH), causes somatotroph proliferation and may have direct actions in fetal/placental development, reproduction and immune function. It exerts its action through high-affinity GHRH receptors present in the anterior pituitary. GSH-1 (GS homeobox 1) is a 264 amino acid hypothalamic nuclear protein that functions as a transcription factor responsible for maintaining GHRH expression as well as playing an important role in pituitary development. Coexpression of CBP leads to significantly enhanced GSH-1-induced GHRH expression, which suggest that CBP may function as a co-activator. Knockdown of GSH-1 mRNA in mice causes a dwarf phenotype, which suggests that certain cases of familial dwarfism may be caused by a mutation of the GSH-1 gene.

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