TMEM59 Antikörper (AA 141-240) (AbBy Fluor® 647)

Produktnummer ABIN1392510

Produktdetails anti-TMEM59 Antikörper (AbBy Fluor® 647)

Target: TMEM59 (Transmembrane Protein 59 (TMEM59))

Bindungsspezifität: AA 141-240

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM59 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TMEM59

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TMEM59

Target: TMEM59 (Transmembrane Protein 59 (TMEM59))

Andere Bezeichnung: TMEM59 (TMEM59 Produkte)

Synonyme: Tmem59 antikoerper, C1orf8 antikoerper, HSPC001 antikoerper, 1110001M20Rik antikoerper, 3110046P06Rik antikoerper, AI256529 antikoerper, D4Ertd20e antikoerper, MTDCF1 antikoerper, ORF18 antikoerper, transmembrane protein 59 antikoerper, tmem59 antikoerper, Tmem59 antikoerper, TMEM59 antikoerper

Hintergrund:

Synonyms: C1orf8, HSPC001, Liver membrane-bound protein, TMEM59, TMEM59 transmembrane protein 59, TMM59_HUMAN, Transmembrane protein 59.

Background: TMEM59 is a 144 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.