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TMEM59 Antikörper (AA 141-240) (AbBy Fluor® 647)

TMEM59 Reaktivität: Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN1392510
  • Target Alle TMEM59 Antikörper anzeigen
    TMEM59 (Transmembrane Protein 59 (TMEM59))
    Bindungsspezifität
    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 141-240
    Reaktivität
    • 14
    • 11
    Maus
    Wirt
    • 25
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TMEM59 Antikörper ist konjugiert mit AbBy Fluor® 647
    Applikation
    • 21
    • 12
    • 12
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TMEM59
    Isotyp
    IgG
    Top Product
    Discover our top product TMEM59 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TMEM59 (Transmembrane Protein 59 (TMEM59))
    Andere Bezeichnung
    TMEM59 (TMEM59 Produkte)
    Synonyme
    Tmem59 antikoerper, C1orf8 antikoerper, HSPC001 antikoerper, 1110001M20Rik antikoerper, 3110046P06Rik antikoerper, AI256529 antikoerper, D4Ertd20e antikoerper, MTDCF1 antikoerper, ORF18 antikoerper, transmembrane protein 59 antikoerper, tmem59 antikoerper, Tmem59 antikoerper, TMEM59 antikoerper
    Hintergrund

    Synonyms: C1orf8, HSPC001, Liver membrane-bound protein, TMEM59, TMEM59 transmembrane protein 59, TMM59_HUMAN, Transmembrane protein 59.

    Background: TMEM59 is a 144 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

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