PCYT2 Antikörper (AA 315-389) (AbBy Fluor® 350)
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- Target Alle PCYT2 Antikörper anzeigen
- PCYT2 (Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2))
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Bindungsspezifität
- AA 315-389
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PCYT2 Antikörper ist konjugiert mit AbBy Fluor® 350
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PCYT2
- Isotyp
- IgG
- Top Product
- Discover our top product PCYT2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- PCYT2 (Phosphate Cytidylyltransferase 2, Ethanolamine (PCYT2))
- Andere Bezeichnung
- PCYT2 (PCYT2 Produkte)
- Synonyme
- ET antikoerper, 1110033E03Rik antikoerper, ethanolamine-phosphate cytidylyltransferase antikoerper, putative ethanolamine-phosphate cytidylyltransferase antikoerper, Ethanolamine-phosphate cytidylyltransferase antikoerper, phosphate cytidylyltransferase 2, ethanolamine antikoerper, phosphate cytidylyltransferase 2, ethanolamine L homeolog antikoerper, Tc00.1047053511727.120 antikoerper, Tb11.01.5730 antikoerper, LINJ_32_0940 antikoerper, LOC5566800 antikoerper, LMJF_32_0890 antikoerper, EDI_013070 antikoerper, EDI_204270 antikoerper, CpipJ_CPIJ009320 antikoerper, Bm1_01855 antikoerper, pcy2 antikoerper, PCYT2 antikoerper, Pcyt2 antikoerper, pcyt2.L antikoerper
- Hintergrund
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Synonyms: CTP, phosphoethanolamine cytidylyltransferase, ET, Ethanolamine-phosphate cytidylyltransferase, Ethanolaminephosphate Cytidyltransferase, PCY2, PCY2_HUMAN, Pcyt2, Phosphate cytidylyltransferase 2 ethanolamine, Phosphorylethanolamine transferase.
Background: Phosphatidylethanolamine (PtdEtn) is a major membrane phospholipid which serves to play a primary role in cell membrane structure and is also involved in cell division, cell signaling, activation, phagocytosis and autophagy. PCYT2 (Phosphorylethanolamine transferase), also known as Ethanolamine-phosphate cytidylyltransferase, is a 389 amino acid protein that catalyzes the formation of CDP-ethanolamine from ethanolamine. This product combined with diacylglycerol form phosphatidylethanolamine via the de novo Kennedy pathway. PCYT2 is expressed at highest levels in heart, liver and skeletal muscle. Elevated levels of MyoD, reduced content of Sp1 and a changed ratio of Sp1 to Sp3 all together stimulate upregulation of PCTY2 transcription during C2C12 muscle cell differentiation. Disruption of the PCYT2 gene in mice leads to death after embryo implantation, establishing the necessity of PCYT2 for murine development.
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