CTNND2 Antikörper (AA 951-1050) (Biotin)
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- Target Alle CTNND2 Antikörper anzeigen
- CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))
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Bindungsspezifität
- AA 951-1050
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CTNND2 Antikörper ist konjugiert mit Biotin
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Applikation
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human delta 2 Catenin
- Isotyp
- IgG
- Top Product
- Discover our top product CTNND2 Primärantikörper
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- Applikationshinweise
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IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))
- Andere Bezeichnung
- CTNND2/delta 2 Catenin (CTNND2 Produkte)
- Synonyme
- CTNND2 antikoerper, Catnd2 antikoerper, Nprap antikoerper, neurojugin antikoerper, GT24 antikoerper, NPRAP antikoerper, ctnnd2 antikoerper, si:dkey-40c17.4 antikoerper, catenin delta 2 antikoerper, delta-catenin antikoerper, catenin delta-2 antikoerper, catenin (cadherin associated protein), delta 2 antikoerper, catenin (cadherin-associated protein), delta 2b antikoerper, CTNND2 antikoerper, BACOIKO001_27 antikoerper, LOC100070792 antikoerper, Ctnnd2 antikoerper, ctnnd2b antikoerper
- Hintergrund
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Synonyms: Catenin cadherin associated protein delta 2, Catenin delta 2, Catenin delta-2, CTND2_HUMAN, CTNND 2, CTNND2, Delta catenin, Delta-catenin, GT 24, GT24, Neural plakophilin related arm repeat protein, Neural plakophilin related armadillo repeat protein, Neural plakophilin-related ARM-repeat protein, Neurojungin, NPRAP
Background: The Alpha-, Beta-, Gamma-, and Delta -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin interacts with E-cadherin associated protein and also associates with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin also complexes with the tumor suppressor protein APC. Gamma-catenin, also known as plakoglobin, is a protein that binds ?catenin and N-cadherin. Gamma-catenin interacts with presenilin 1 and is expressed in the brain. The gene encoding Gamma-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding Gamma-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. In addition, the transmembrane phosphatase PTPm associates with catenin/ cadherin complexes and may regulate complex signaling.
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