Thimet Oligopeptidase 1 Antikörper (AA 51-150) (Biotin)

Produktnummer ABIN1392721

Produktdetails anti-Thimet Oligopeptidase 1 Antikörper (Biotin)

Target: Thimet Oligopeptidase 1 (THOP1)

Bindungsspezifität: AA 51-150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Thimet Oligopeptidase 1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Thimet Oligopeptidase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Thimet Oligopeptidase 1

Target: Thimet Oligopeptidase 1 (THOP1)

Andere Bezeichnung: THOP1/Thimet Oligopeptidase (THOP1 Produkte)

Hintergrund:

Synonyms: Endopeptidase 24.15, EP24.15, MEPD_HUMAN, MP78, Thimet oligopeptidase 1, Thimet oligopeptidase, Thop1, THOP1_HUMAN, EC 3.4.24.15.

Background: Thimet oligopeptidase, also designated soluble metallo-endopeptidase, is a cytoplasmic protein belonging to the peptidase M3 family. The gene for the protein maps against chromosome 19q13.3. Thimet oligopeptidase can degrade the b-Amyloid precursor protein and generate amyloidogenic fragments. It is important in cytoplasmic peptide degradation and involved in metabolism of neuropeptides that are less than 20 amino acids in length. Thimet oligopeptidase is highly expressed in testis but can also be detected in liver, lung and kidney.