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AKR7A2 Antikörper (AA 81-150) (Biotin)

AKR7A2 Reaktivität: Human ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1392859
  • Target Alle AKR7A2 Antikörper anzeigen
    AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))
    Bindungsspezifität
    • 14
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 81-150
    Reaktivität
    • 51
    • 17
    • 12
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 40
    • 11
    Kaninchen
    Klonalität
    • 42
    • 9
    Polyklonal
    Konjugat
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AKR7A2 Antikörper ist konjugiert mit Biotin
    Applikation
    • 23
    • 13
    • 13
    • 10
    • 9
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human AKR7A2
    Isotyp
    IgG
    Top Product
    Discover our top product AKR7A2 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))
    Andere Bezeichnung
    SSA reductase/AKR7A2 (AKR7A2 Produkte)
    Synonyme
    AFAR antikoerper, AFAR1 antikoerper, AFB1-AR1 antikoerper, AKR7 antikoerper, Aiar antikoerper, akr7a2 antikoerper, aldo-keto reductase family 7 member A2 antikoerper, aldo-keto reductase family 7, member A2 antikoerper, aldo-keto reductase family 7, member A2 L homeolog antikoerper, AKR7A2 antikoerper, Akr7a2 antikoerper, akr7a2.L antikoerper
    Hintergrund

    Synonyms: AFAR, AFAR1, AFB1 aldehyde reductase 1, AFB1 AR1, AFB1-AR 1, AFB1AR1, Aflatoxin aldehyde reductase, Aflatoxin B1 aldehyde reductase member 2, Aflatoxin beta1 aldehyde reductase, Aiar, AKR7, Akr7a2, Aldo keto reductase family 7, Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase, Aldo keto reductase family 7 member A2, Aldoketoreductase 7, ARK72_HUMAN, SSA reductase, SSA reductase, Succinic semialdehyde reductase.

    Background: The aldo-keto reductase 7 (AKR7) family includes AKR7A2, AKR7A3 and AKR7A4 in human, AKR7A5 in mouse and AKR7A2 in rat, all of which function in the metabolism of aflatoxin B(1) and other dicarbonyl-containing compounds. More specifically, AKR7A proteins are involved in the metabolism of compounds with ketone groups on adjacent carbon atoms in a broad range of tissues, notably the liver. The human AKR7A2 gene maps to human chromosome 1p35-36, a region frequently deleted in sporadic colorectal cancer. The functional significance of this correlation lies in the constitutive expression of AKR7A2 in human liver to eliminate aflatoxin (an environmental carcinogen), thus acting as an endogenous chemo-preventative agent.

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