AKR7A2 Antikörper (AA 81-150) (Biotin)

Produktnummer ABIN1392859

Produktdetails anti-AKR7A2 Antikörper (Biotin)

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Bindungsspezifität: AA 81-150

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR7A2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AKR7A2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu AKR7A2

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Andere Bezeichnung: SSA reductase/AKR7A2 (AKR7A2 Produkte)

Synonyme: AFAR antikoerper, AFAR1 antikoerper, AFB1-AR1 antikoerper, AKR7 antikoerper, Aiar antikoerper, akr7a2 antikoerper, aldo-keto reductase family 7 member A2 antikoerper, aldo-keto reductase family 7, member A2 antikoerper, aldo-keto reductase family 7, member A2 L homeolog antikoerper, AKR7A2 antikoerper, Akr7a2 antikoerper, akr7a2.L antikoerper

Hintergrund:

Synonyms: AFAR, AFAR1, AFB1 aldehyde reductase 1, AFB1 AR1, AFB1-AR 1, AFB1AR1, Aflatoxin aldehyde reductase, Aflatoxin B1 aldehyde reductase member 2, Aflatoxin beta1 aldehyde reductase, Aiar, AKR7, Akr7a2, Aldo keto reductase family 7, Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase, Aldo keto reductase family 7 member A2, Aldoketoreductase 7, ARK72_HUMAN, SSA reductase, SSA reductase, Succinic semialdehyde reductase.

Background: The aldo-keto reductase 7 (AKR7) family includes AKR7A2, AKR7A3 and AKR7A4 in human, AKR7A5 in mouse and AKR7A2 in rat, all of which function in the metabolism of aflatoxin B(1) and other dicarbonyl-containing compounds. More specifically, AKR7A proteins are involved in the metabolism of compounds with ketone groups on adjacent carbon atoms in a broad range of tissues, notably the liver. The human AKR7A2 gene maps to human chromosome 1p35-36, a region frequently deleted in sporadic colorectal cancer. The functional significance of this correlation lies in the constitutive expression of AKR7A2 in human liver to eliminate aflatoxin (an environmental carcinogen), thus acting as an endogenous chemo-preventative agent.