NDUFS7 Antikörper (AA 101-160) (AbBy Fluor® 488)
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- Target Alle NDUFS7 Antikörper anzeigen
- NDUFS7 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 7, 20kDa (NADH-Coenzyme Q Reductase) (NDUFS7))
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Bindungsspezifität
- AA 101-160
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NDUFS7 Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Cow,Pig,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NDUFS7
- Isotyp
- IgG
- Top Product
- Discover our top product NDUFS7 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- NDUFS7 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 7, 20kDa (NADH-Coenzyme Q Reductase) (NDUFS7))
- Andere Bezeichnung
- NDUFS7 (NDUFS7 Produkte)
- Synonyme
- 1010001M04Rik antikoerper, CI-20 antikoerper, CI-20KD antikoerper, MY017 antikoerper, PSST antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 7 antikoerper, NADH:ubiquinone oxidoreductase core subunit S7 antikoerper, Ndufs7 antikoerper, NDUFS7 antikoerper
- Hintergrund
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Synonyms: CI 20, CI-20kD, Complex I 20 kDa subunit, Complex I mitochondrial respiratory chain 20 KD subunit, Complex I-20kD, MGC120002, MY017, NADH coenzyme Q reductase, NADH dehydrogenase ubiquinone Fe S protein 7 20 kDa NADH coenzyme Q reductase, NADH dehydrogenase ubiquinone FeS protein 7, 20 kDa NADHcoenzyme Q reductase, NADH dehydrogenase ubiquinone FeS protein7, 20 kDa NADHcoenzyme Q reductase, NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, NADH-ubiquinone oxidoreductase 20 kDa subunit, NADH:ubiquinone oxidoreductase PSST subunit, NADHcoenzyme Q reductase, Ndufs7, NDUS7_HUMAN, PSST, PSST subunit.
Background: Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity. Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.
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