NMNAT1 Antikörper (AbBy Fluor® 350)

Produktnummer ABIN1393029

Produktdetails anti-NMNAT1 Antikörper (AbBy Fluor® 350)

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMNAT1 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nmnat1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NMNAT1

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Andere Bezeichnung: Nmnat1 (NMNAT1 Produkte)

Hintergrund:

Synonyms: NaMN adenylyltransferase 1, Nicotinamide mononucleotide adenylyltransferase 1, nicotinamide nucleotide adenylyltransferase 1, nicotinate nucleotide adenylyltransferase 1, Nicotinate-nucleotide adenylyltransferase 1, NMN adenylyltransferase 1, NMNA1_HUMAN, Nmnat 1, Nmnat1, Nmnat-1, OTTHUMP00000001731, OTTHUMP00000001732, OTTHUMP00000035892, PNAT 1, PNAT1, pyridine nucleotide adenylyltransferase 1.

Background: Nicotinamide adenine dinucleotide (NMNAT) is an essential cofactor involved in fundamental processes in cell metabolism. NMNAT plays a key role in NAD(+) biosynthesis, catalysing the condensation of nicotinamide mononucleotide and ATP, and yielding NAD(+) and pyrophosphate. NMNAT appears to be a substrate of nuclear kinases and contains at least three potential phosphorylation sites. The interaction of NMNAT with nuclear proteins is likely to be modulated by phosphorylation. NMNAT is widely expressed with highest levels in skeletal muscle, heart, liver and kidney.