EBF2 Antikörper (AA 331-400) (Biotin)
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- Target Alle EBF2 Antikörper anzeigen
- EBF2 (Early B-Cell Factor 2 (EBF2))
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Bindungsspezifität
- AA 331-400
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EBF2 Antikörper ist konjugiert mit Biotin
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Applikation
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human EBF2
- Isotyp
- IgG
- Top Product
- Discover our top product EBF2 Primärantikörper
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anti-Early B-Cell Factor 2 (EBF2) (AA 53-254) antibody
EBF2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Early B-Cell Factor 2 (EBF2) antibodyEBF2 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Early B-Cell Factor 2 (EBF2) (AA 405-454) antibodyEBF2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Affe, Schwein, Fledermaus, Huhn WB Wirt: Kaninchen Polyclonal unconjugated
anti-Early B-Cell Factor 2 (EBF2) (AA 359-408) antibodyEBF2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund, Affe, Schwein, Fledermaus, Huhn, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Early B-Cell Factor 2 (EBF2) (AA 285-536) antibodyEBF2 Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Early B-Cell Factor 2 (EBF2) (Middle Region) antibodyEBF2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- EBF2 (Early B-Cell Factor 2 (EBF2))
- Andere Bezeichnung
- EBF2 (EBF2 Produkte)
- Hintergrund
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Synonyms: COE 2, COE2, Collier Olf and EBF 2, Early B cell factor 2, EBF 2, FLJ11500, Metencephalon mesencephalnon olfactory transcription factor 1, O/E 3, O/E3, OE 3, OE3, OLF 1/EBF like 3, Transcription factor COE2, COE2_HUMAN.
Background: Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins, whose members are all helix-loop-helix transcription factors. EBF2 is a transcription factor which, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, activates the decoy receptor for RANKL, OPG, in osteoblasts. OPG, in turn, regulates osteoclast differentiation. Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, along with reduced bone mass and an increase in osteoclasts. Localized to the nucleus, EBF2 forms a homodimer or a heterodimer with a related family member.
- Gen-ID
- 64641
- UniProt
- Q9HAK2
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