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SPG21 Antikörper (AA 151-250) (AbBy Fluor® 555)

SPG21 Reaktivität: Human WB, IF (p), IF (cc) Wirt: Kaninchen Polyclonal AbBy Fluor® 555
Produktnummer ABIN1393307
  • Target Alle SPG21 Antikörper anzeigen
    SPG21 (Spastic Paraplegia 21 (SPG21))
    Bindungsspezifität
    • 14
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 151-250
    Reaktivität
    • 26
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 23
    • 3
    Kaninchen
    Klonalität
    • 24
    • 2
    Polyklonal
    Konjugat
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPG21 Antikörper ist konjugiert mit AbBy Fluor® 555
    Applikation
    • 19
    • 12
    • 12
    • 10
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Homologie
    Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SPG21
    Isotyp
    IgG
    Top Product
    Discover our top product SPG21 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    SPG21 (Spastic Paraplegia 21 (SPG21))
    Andere Bezeichnung
    SPG21 (SPG21 Produkte)
    Synonyme
    ACP33 antikoerper, GL010 antikoerper, MAST antikoerper, BM-019 antikoerper, C78576 antikoerper, D9Wsu18e antikoerper, Maspardin antikoerper, wu:fd07h02 antikoerper, zgc:73091 antikoerper, SPG21, maspardin antikoerper, spastic paraplegia 21 (autosomal recessive, Mast syndrome) antikoerper, SPG21, maspardin S homeolog antikoerper, SPG21 antikoerper, Spg21 antikoerper, spg21.S antikoerper, spg21 antikoerper
    Hintergrund

    Synonyms: Acid cluster protein 33, ACP33, BM019, BM-019, GL010, MAST, Maspardin, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, SPG21 antibody, SPG21_HUMAN.

    Background: Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed. Belonging to the AB hydrolase superfamily, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network. It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation. Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. The gene encoding Maspardin is encoded by human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome.

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