Ataxin 10 Antikörper (AA 21-120) (AbBy Fluor® 555)
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- Target Alle Ataxin 10 (ATXN10) Antikörper anzeigen
- Ataxin 10 (ATXN10)
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Bindungsspezifität
- AA 21-120
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Ataxin 10 Antikörper ist konjugiert mit AbBy Fluor® 555
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Dog,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ATXN10/SCA10
- Isotyp
- IgG
- Top Product
- Discover our top product ATXN10 Primärantikörper
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Ataxin 10 (ATXN10)
- Andere Bezeichnung
- ATXN10/SCA10 (ATXN10 Produkte)
- Synonyme
- ATXN10 antikoerper, MGC97716 antikoerper, atxn10 antikoerper, Ataxin-10 antikoerper, si:dkeyp-15g12.2 antikoerper, E46L antikoerper, HUMEEP antikoerper, SCA10 antikoerper, Sca10 antikoerper, AI325283 antikoerper, C77170 antikoerper, E46 antikoerper, TEG-169 antikoerper, Tex169 antikoerper, ataxin 10 antikoerper, ATXN10 antikoerper, atxn10 antikoerper, Atxn10 antikoerper
- Hintergrund
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Synonyms: Ataxin 10, Ataxin-10, ATX10_HUMAN, Atxn10, Brain protein E46 homolog, E46L, FLJ37990, HUMEEP, Like mouse brain protein E46, SCA10, Spinocerebellar ataxia 10, Spinocerebellar ataxia type 10 protein.
Background: Spinocerebellar ataxia (SCA) is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss. SCA is caused by the expansion of a translated CAG repeat, encoding a polyglutamine tract in SCA gene products, known as ataxins. The ataxin proteins are ubiquitously expressed in nervous tissue, but are primarily detected in cerebellum, brain stem and spinal cord in the central nervous system. Ataxin-10 is a cytoplasmic protein that belongs to the family of armadillo repeat proteins. A loss of ataxin-10 in primary neuronal cells causes increased apoptosis of cerebellar neurons. Ataxin-10 interacts with p110, an O-Linked beta-N-acetylglucosamine transferase, and may be important in the regulation of intracellular glycosylation levels and homeostasis in the brain. Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant disorder that causes cerebellar ataxia and seizures. SCA10 is caused by an expansion of an ATTCT pentanucleotide repeat in intron 9 of the ataxin-10 gene.
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