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CBLN2 Antikörper (AA 151-224) (AbBy Fluor® 555)

CBLN2 Reaktivität: Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 555
Produktnummer ABIN1393487
  • Target Alle CBLN2 Produkte
    CBLN2 (Cerebellin 2 Precursor (CBLN2))
    Bindungsspezifität
    • 14
    • 11
    • 8
    • 7
    • 1
    • 1
    • 1
    AA 151-224
    Reaktivität
    • 28
    • 25
    • 20
    • 2
    • 1
    • 1
    Ratte
    Wirt
    • 42
    Kaninchen
    Klonalität
    • 42
    Polyklonal
    Konjugat
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CBLN2 Antikörper ist konjugiert mit AbBy Fluor® 555
    Applikation
    • 35
    • 20
    • 13
    • 12
    • 12
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CBLN2
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CBLN2 (Cerebellin 2 Precursor (CBLN2))
    Andere Bezeichnung
    CBLN2 (CBLN2 Produkte)
    Synonyme
    MGC64397 antikoerper, si:dkey-82k12.11 antikoerper, 6330593N19Rik antikoerper, A730004O05 antikoerper, zgc:163051 antikoerper, cerebellin 2 precursor antikoerper, cerebellin 2 precursor L homeolog antikoerper, cerebellin 2a precursor antikoerper, cerebellin 2 precursor protein antikoerper, cerebellin 2b precursor antikoerper, CBLN2 antikoerper, cbln2.L antikoerper, cbln2 antikoerper, cbln2a antikoerper, Cbln2 antikoerper, cbln2b antikoerper
    Hintergrund

    Synonyms: A730004O05, Cbln2, CBLN2_HUMAN, Cerebellin 2, Cerebellin 2 precursor, Cerebellin-2, OTTHUMP00000163726.

    Background: Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3), and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. CER and it metabolite des-Ser1-cerebellin are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other?s degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for CER in the pathology of these diseases.

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