CBLN4 Antikörper (AA 101-201) (Biotin)

Produktnummer ABIN1393495

Produktdetails anti-CBLN4 Antikörper (Biotin)

Target: CBLN4 (Cerebellin 4 Precursor (CBLN4))

Bindungsspezifität: AA 101-201

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBLN4 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CBLN4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu CBLN4

Target: CBLN4 (Cerebellin 4 Precursor (CBLN4))

Andere Bezeichnung: CBLN4 (CBLN4 Produkte)

Synonyme: zgc:172190 antikoerper, cerebellin-4 antikoerper, CBLNL1 antikoerper, AI848962 antikoerper, cerebellin 4 precursor antikoerper, cerebellin 4 precursor L homeolog antikoerper, cerebellin 4 precursor protein antikoerper, CBLN4 antikoerper, cbln4 antikoerper, cbln4.L antikoerper, Cbln4 antikoerper

Hintergrund:

Synonyms: CBLN 4, CBLNL1, Cerebellin 4, Cerebellin 4 precursor, Cerebellin like glycoprotein 1, Cerebellin precursor like 1, Cerebellin4, CBLN4_HUMAN.

Background: Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor called Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3) and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. Cerebellin and its metabolite, des-Ser(1)Cer, are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other?s degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of Cerebellin have been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for Cerebellin in the pathology of these diseases.