FNBP1L Antikörper (AA 101-200) (Biotin)

Produktnummer ABIN1393645

Produktdetails anti-FNBP1L Antikörper (Biotin)

Target: FNBP1L (Formin Binding Protein 1-Like (FNBP1L))

Bindungsspezifität: AA 101-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FNBP1L Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FNBP1L/TOCA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu FNBP1L

Target: FNBP1L (Formin Binding Protein 1-Like (FNBP1L))

Andere Bezeichnung: FNBP1L/TOCA1 (FNBP1L Produkte)

Synonyme: C1orf39 antikoerper, TOCA1 antikoerper, 2610318I01Rik antikoerper, AW548221 antikoerper, RGD1305386 antikoerper, Toca-1 antikoerper, zgc:100923 antikoerper, toca1 antikoerper, toca-1 antikoerper, MGC132162 antikoerper, fnbp1l antikoerper, formin binding protein 1 like antikoerper, formin binding protein 1-like antikoerper, formin binding protein 1 like L homeolog antikoerper, formin binding protein 1 like S homeolog antikoerper, FNBP1L antikoerper, Fnbp1l antikoerper, fnbp1l antikoerper, fnbp1l.L antikoerper, fnbp1l.S antikoerper

Hintergrund:

Synonyms: C1orf39, FBP1L_HUMAN, FNBP 1L, fnbp1l, Formin binding protein 1 like, Formin-binding protein 1-like, TOCA 1, Toca-1, TOCA1, Transducer of Cdc42 dependent actin assembly 1 , Transducer of Cdc42 dependent actin assembly protein 1, Transducer of Cdc42-dependent actin assembly protein 1.

Background: TOCA-1 is a 605 amino acid protein that localizes to the cytoplasm and the cytoskeleton, as well as to cytoplasmic vesicles and the cell membrane, and contains one FCH domain, one REM repeat and one SH3 domain. Existing as multiple alternatively spliced isoforms, TOCA-1 interacts with CDC42 and is required for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. Additionally, TOCA-1 is involved in membrane invagination, tubule formation and Actin polymerization. The gene encoding TOCA-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome.