GDF6 Antikörper (AA 336-410) (Biotin)

Produktnummer ABIN1393657

Produktdetails anti-GDF6 Antikörper (Biotin)

Target: GDF6 (Growth Differentiation Factor 6 (GDF6))

Bindungsspezifität: AA 336-410

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF6 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GDF6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GDF6

Target: GDF6 (Growth Differentiation Factor 6 (GDF6))

Andere Bezeichnung: GDF6 (GDF6 Produkte)

Synonyme: BMP13 antikoerper, CDMP2 antikoerper, KFM antikoerper, KFS antikoerper, KFS1 antikoerper, KFSL antikoerper, LCA17 antikoerper, MCOP4 antikoerper, MCOPCB6 antikoerper, SCDO4 antikoerper, SGM1 antikoerper, GDF16 antikoerper, gdf16 antikoerper, CDMP-2 antikoerper, gdf6 antikoerper, rdr antikoerper, sb:cb278 antikoerper, bmp13 antikoerper, cdmp2 antikoerper, gdf-6 antikoerper, kfs antikoerper, kfsl antikoerper, sgm1 antikoerper, growth differentiation factor 6 antikoerper, growth differentiation factor 6a antikoerper, growth differentiation factor 6 S homeolog antikoerper, GDF6 antikoerper, Gdf6 antikoerper, gdf6 antikoerper, gdf6a antikoerper, gdf6.S antikoerper

Hintergrund:

Synonyms: bmp 13, bmp13, bmp-13, Cartilage Derived Morphogenetic Protein 2, cdmp 2, CDMP2, gdf 6, GDF16 , Growth dferentiation factor 6, Growth/dferentiation factor 6, GDF6_HUMAN.

Background: Growth/differentiation factors (GDFs) are members of the TGF superfamily (1,2). Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis (1). GDF-1 expression is almost exclusively restricted to the central nervous system and mediates cell differentiation events during embryonic development (3). Neither GDF-3 (Vgr-2) nor GDF-9 contains the conserved cysteine residue which is found in most other TGF superfamily members. GDF-3 is detectable in bone marrow, spleen, thymus and adipose tissue, whereas GDF-9 has only been detected in ovary (4). GDF-5 (also designated CDMP-1) has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. (5). GDF-5 mutations have been identified in mice with the mutation brachypodism (bp), a mutation which affects the length and number of bones in limbs (6). GDF-6 and GDF-7 are closely related to GDF-5 (6). GDF-8 has been shown to be a negative regulator of skeletal muscle mass (1).