ITM2C Antikörper (AA 3-88) (AbBy Fluor® 350)
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- Target Alle ITM2C Antikörper anzeigen
- ITM2C (Integral Membrane Protein 2C (ITM2C))
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Bindungsspezifität
- AA 3-88
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ITM2C Antikörper ist konjugiert mit AbBy Fluor® 350
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ITM2C
- Isotyp
- IgG
- Top Product
- Discover our top product ITM2C Primärantikörper
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anti-Integral Membrane Protein 2C (ITM2C) (AA 27-55), (N-Term) antibody
ITM2C Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB36714 unconjugated
anti-Integral Membrane Protein 2C (ITM2C) (AA 1-230) antibodyITM2C Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Integral Membrane Protein 2C (ITM2C) (AA 101-150) antibodyITM2C Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schaf, Fledermaus, Affe, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ITM2C (Integral Membrane Protein 2C (ITM2C))
- Andere Bezeichnung
- ITM2C (ITM2C Produkte)
- Hintergrund
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Synonyms: BRI3, BRICD2C, BRICHOS domain containing 2C, Cerebral protein 14, CT-BRI3, E25, E25C , Integral membrane protein 2C, Integral membrane protein 3, Itm2c, ITM2C_HUMAN, ITM3 antibodyNPD018, Transmembrane protein BRI3.
Background: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
- Gen-ID
- 81618
- UniProt
- Q9NQX7
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