KIRREL3 Antikörper (AA 351-450) (Biotin)

Produktnummer ABIN1393777

Produktdetails anti-KIRREL3 Antikörper (Biotin)

Target: KIRREL3 (Kin of IRRE Like 3 (KIRREL3))

Bindungsspezifität: AA 351-450

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIRREL3 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KIRREL3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu KIRREL3

Target: KIRREL3 (Kin of IRRE Like 3 (KIRREL3))

Andere Bezeichnung: KIRREL3 (KIRREL3 Produkte)

Synonyme: KIRRE antikoerper, MRD4 antikoerper, NEPH2 antikoerper, PRO4502 antikoerper, 1500010O20Rik antikoerper, 2900036G11Rik antikoerper, SST4 antikoerper, mKIAA1867 antikoerper, kirre like nephrin family adhesion molecule 3 antikoerper, kin of IRRE like 3 (Drosophila) antikoerper, KIRREL3 antikoerper, Kirrel3 antikoerper

Hintergrund:

Synonyms: Kin of IRRE like 3 Drosophila, Kin of IRRE like 3, Kin of irregular chiasm like protein 3 , KIRRE, KIRREL 3, KIRREL-3, MRD4, NEPH2, Nephrin like 2, PRO19814, PRO4502, yUNQ5923, KIRR3_HUMAN.

Background: NEPH2 is a 778 amino acid single-pass type I membrane protein that belongs to the nephrin-like protein family and immunoglobulin superfamily. Expressed in both fetal and adult brain, as well as podocytes of kidney glomeruli, NEPH2 contains five Ig-like C2-type (immunoglobulin-like) domains and is thought to plaly a role in the hematopoetic supportive capacity of stroma cells. NEPH2 undergoes alternative splicing to produce two isoforms and contains a C-terminal cytoplasmic domain which it uses to interact with Podocin, a podocyte protein involved in ultrafiltration. Defects in the gene encoding NEPH2 are associated with mental retardation autosomal dominant type 4 (MRD4).