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MTPN Antikörper (AA 41-118) (AbBy Fluor® 555)

MTPN Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 555
Produktnummer ABIN1393937
  • Target Alle MTPN Antikörper anzeigen
    MTPN (Myotrophin (MTPN))
    Bindungsspezifität
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 41-118
    Reaktivität
    • 24
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 21
    • 4
    Kaninchen
    Klonalität
    • 23
    • 2
    Polyklonal
    Konjugat
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MTPN Antikörper ist konjugiert mit AbBy Fluor® 555
    Applikation
    • 25
    • 12
    • 12
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Myotrophin/GCDP
    Isotyp
    IgG
    Top Product
    Discover our top product MTPN Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MTPN (Myotrophin (MTPN))
    Andere Bezeichnung
    Myotrophin/GCDP (MTPN Produkte)
    Synonyme
    MGC76285 antikoerper, GCDP antikoerper, V-1 antikoerper, Gcdp antikoerper, wu:fa10f07 antikoerper, zgc:64078 antikoerper, 5033418D15Rik antikoerper, V1 antikoerper, myotrophin antikoerper, myotrophin S homeolog antikoerper, mtpn antikoerper, MTPN antikoerper, Mtpn antikoerper, mtpn.S antikoerper
    Hintergrund

    Synonyms: FLJ31098, FLJ99857, GCDP, Granule cell dferentiation protein, MTPN, MTPN_HUMAN, Myotrophin, Protein V 1, Protein V-1, V 1, MTPN_HUMAN.

    Background: Myotrophin (V-1 protein) is a ubiquitously expressed cytoplasmic protein that can translocate to the nucleus during sustained NFkB activation. The gene encoding for this protein localizes to chromosome 7q33. Myotrophin may be involved in cerebellar morphogenesis and contains an acetylated N-terminus and 2.5 internal 33 amino acid ankyrin repeats. It is important in the differentiation of cerebellar neurons, particularly of granule cells. The 117 amino acid protein has been associated with, and able to induce, cardiac hypertrophy. Myotrophin increases protooncogene, ANF and Beta-Myosin heavy chain transcript levels. Myotrophin is upregulated when myocytes undergo cyclic stretch or are treated with tumor necrosis factor Alpha (TNF Alpha) or interleukin-1Beta. Highest levels of Myotrophin are detected in brain and lowest levels in skeletal muscle.

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