PNMA1 Antikörper (AA 165-270) (AbBy Fluor® 488)

Produktnummer ABIN1394140

Produktdetails anti-PNMA1 Antikörper (AbBy Fluor® 488)

Target: PNMA1 (Paraneoplastic Antigen MA1 (PNMA1))

Bindungsspezifität: AA 165-270

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNMA1 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PNMA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PNMA1

Target: PNMA1 (Paraneoplastic Antigen MA1 (PNMA1))

Andere Bezeichnung: PNMA1 (PNMA1 Produkte)

Synonyme: PNMA1 antikoerper, 5730402C15Rik antikoerper, MA1 antikoerper, PNMA family member 1 antikoerper, paraneoplastic antigen MA1 antikoerper, paraneoplastic Ma antigen 1 antikoerper, PNMA1 antikoerper, Pnma1 antikoerper

Hintergrund:

Synonyms: 37 kDa neuronal protein, MA1, Paraneoplastic antigen MA1,

Background: Paraneoplastic neurological disorders (PNDs) are rare syndromes that are caused by, or associated with, an underlying neoplasm. The most common neoplasm among young male patients is testicular cancer, but the leading cause among other patients is lung cancer. Most PNDs are caused by an immune response against onconeural antigens, causing progressive neurological damage. The paraneoplastic antigen MA family contains three known members: MA1, MA2 and MA3. MA1, also designated neuron- and testis-specific protein 1, is a nucleolar protein in normal cells but localizes to the cytoplasm of tumor cells. MA2, also designated onconeuronal antigen MA2, is a nucleolar protein expressed in brain and testis. MA3 is highly expressed in brain and testis and is expressed at low levels in heart, trachea and kidney.