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SLITRK2 Antikörper (AA 311-410) (Biotin)

SLITRK2 Reaktivität: Human WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1394305
  • Target Alle SLITRK2 Antikörper anzeigen
    SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 311-410
    Reaktivität
    • 48
    • 9
    • 9
    • 3
    • 3
    • 3
    • 3
    Human
    Wirt
    • 48
    Kaninchen
    Klonalität
    • 48
    Polyklonal
    Konjugat
    • 12
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SLITRK2 Antikörper ist konjugiert mit Biotin
    Applikation
    • 43
    • 25
    • 13
    • 13
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SLITRK2
    Isotyp
    IgG
    Top Product
    Discover our top product SLITRK2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))
    Andere Bezeichnung
    SLITRK2 (SLITRK2 Produkte)
    Synonyme
    slitrk2 antikoerper, CXorf2 antikoerper, SLITL1 antikoerper, A930040J07 antikoerper, RGD1561361 antikoerper, SLIT and NTRK-like family, member 2 antikoerper, SLIT and NTRK like family member 2 antikoerper, SLITRK2 antikoerper, slitrk2 antikoerper, Slitrk2 antikoerper
    Hintergrund

    Synonyms: CXorf2, KIAA1854, SLIK2_HUMAN, SLIT and NTRK like protein 2, SLIT and NTRK-like protein 2, SLITL1, SLITRK 2, Slitrk2.

    Background: SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK2 (SLIT and NTRK-like protein 2) is a 845 amino acid single-pass type I membrane protein that contains 14 LRR (leucine-rich) repeats and is expressed in neural tissues, with highest levels found in adult cerebral cortex. Overexpression of SLITRK2 leads to inhibition of unipolar neurites in cultured cells, suggesting that it suppresses neurite outgrowth. Inhibitory activity of SLITRK2 is localized to its C-terminal intracellular domain and without this region the protein induces neurite outgrowth. Variants in the gene encoding SLITRK2 may contribute to the development of bipolar disorder, autism spectrum disorder and schizophrenia. There are two isoforms of SLITRK2 that are produced as a result of alternative splicing events.

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