SORCS2 Antikörper (AA 201-300) (AbBy Fluor® 488)
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- Target Alle SORCS2 Antikörper anzeigen
- SORCS2 (Sortilin-Related VPS10 Domain Containing Receptor 2 (SORCS2))
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Bindungsspezifität
- AA 201-300
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SORCS2 Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SORCS2
- Isotyp
- IgG
- Top Product
- Discover our top product SORCS2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- SORCS2 (Sortilin-Related VPS10 Domain Containing Receptor 2 (SORCS2))
- Andere Bezeichnung
- SORCS2 (SORCS2 Produkte)
- Synonyme
- SORCS2 antikoerper, N28137 antikoerper, mKIAA1329 antikoerper, sortilin related VPS10 domain containing receptor 2 antikoerper, VPS10 domain-containing receptor SorCS2 antikoerper, sortilin-related VPS10 domain containing receptor 2 antikoerper, SORCS2 antikoerper, LOC100467197 antikoerper, sorcs2 antikoerper, Sorcs2 antikoerper
- Hintergrund
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Synonyms: KIAA1329, SORCS 2, Sortilin related VPS10 domain containing receptor 2, VPS10 domain receptor protein, VPS10 domain receptor protein SORCS 2, SORC2_HUMAN.
Background: There are three SorCS genes that have diverse, partially overlapping functions in the central nervous system. In the developing and mature central nervous system, SorCS1, SorCS2 and SorCS3 genes are expressed in a combinatorial, non-overlapping pattern. SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, based on a common VPS10 domain, which is the hallmark of the SorCS receptor family. SorCS2 (sortilin-related VPS10 domain containing receptor 2) is a 1,150 amino acid single-pass type I membrane protein that is highly expressed in brain and kidney. Containing six BNR repeats and a single PKD domain, SorCS2 is encoded by a gene that maps to human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
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