NTSR2 Antikörper (AA 151-250) (Biotin)

Produktnummer ABIN1394599

Produktdetails anti-NTSR2 Antikörper (Biotin)

Target: NTSR2 (Neurotensin Receptor 2 (NTSR2))

Bindungsspezifität: AA 151-250

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NTSR2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Neurotensin Receptor 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu NTSR2

Target: NTSR2 (Neurotensin Receptor 2 (NTSR2))

Andere Bezeichnung: Neurotensin Receptor 2 (NTSR2 Produkte)

Synonyme: NTSR2 antikoerper, NTR2 antikoerper, NT2R antikoerper, NTRL antikoerper, neurotensin receptor 2 antikoerper, NTSR2 antikoerper, Ntsr2 antikoerper

Hintergrund:

Synonyms: Levocabastine sensitive neurotensin receptor, Levocabastine-sensitive neurotensin receptor, Neurotensin receptor type 2, NT R 2, NT-R-2, NTR2, NTR2 receptor, NTR2_HUMAN, Ntsr2.

Background: Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNF?in an ERK1/2 and Akt kinase-dependent manner.