GPR125 Antikörper (AA 422-530) (Biotin)

Produktnummer ABIN1394701

Produktdetails anti-GPR125 Antikörper (Biotin)

Target: GPR125 (G Protein-Coupled Receptor 125 (GPR125))

Bindungsspezifität: AA 422-530

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR125 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPR125

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GPR125

Target: GPR125 (G Protein-Coupled Receptor 125 (GPR125))

Andere Bezeichnung: GPR125 (GPR125 Produkte)

Synonyme: PGR21 antikoerper, TEM5L antikoerper, 3830613O22Rik antikoerper, AU044632 antikoerper, Tem5-like antikoerper, GPR125 antikoerper, Gpr125 antikoerper, adhesion G protein-coupled receptor A3 antikoerper, adhesion G protein-coupled receptor A3-like antikoerper, ADGRA3 antikoerper, Adgra3 antikoerper, ADGRA3L antikoerper, adgra3 antikoerper

Hintergrund:

Synonyms: FLJ38547, G protein coupled receptor 125, PGR21, Probable G protein coupled receptor 125 precursor, TEM5 like, TEM5L, GP125_HUMAN, GPCR125.

Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR125 (G protein-coupled receptor 125), also known as PGR21 or TEM5L, is a 1,321 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and the LN-TM7 subfamily. Considered a novel orphan adhesion-type G-protein-coupled receptor, GPR125 has five leucine rich repeats (LRR), an immunoglobulin (Ig) domain and a GPS domain. GPR125 may play a functional role in choroidal and hippocampal response to brain injury. It is also suggested that GPR125 may be a marker for spermatogonial stem cells. Four isoforms of GPR125 exists due to alternative splicing events.