GDE1 Antikörper (AA 231-331) (AbBy Fluor® 647)
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- Target Alle GDE1 Antikörper anzeigen
- GDE1 (Glycerophosphodiester Phosphodiesterase 1 (GDE1))
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Bindungsspezifität
- AA 231-331
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GDE1 Antikörper ist konjugiert mit AbBy Fluor® 647
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Dog,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MIR16/GDE1
- Isotyp
- IgG
- Top Product
- Discover our top product GDE1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- GDE1 (Glycerophosphodiester Phosphodiesterase 1 (GDE1))
- Andere Bezeichnung
- MIR16/GDE1 (GDE1 Produkte)
- Synonyme
- zgc:56068 antikoerper, zgc:77135 antikoerper, 363E6.2 antikoerper, MIR16 antikoerper, 1200003M13Rik antikoerper, Mir16 antikoerper, RGS16 antikoerper, glycerophosphodiester phosphodiesterase 1 antikoerper, glycerophosphodiester phosphodiesterase 1 L homeolog antikoerper, gde1 antikoerper, gde1.L antikoerper, GDE1 antikoerper, Gde1 antikoerper
- Hintergrund
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Synonyms: EC 3.1.4.44, GDE1, Glycerophosphodiester phosphodiesterase 1, Membrane interacting protein of RGS16, RGS16 interacting membrane protein, GDE1_HUMAN.
Background: GDE1 is a 331 amino acid multi-pass membrane protein that localizes to both the membrane and the cytoplasm and contains one GDPD domain. Expressed in a wide variety of tissues, GDE1 uses magnesium as a cofactor to catalyze the conversion of 1-(sn-glycero-3-phospho)-1D-myo-inositol to myo-inositol and sn-glycerol 3-phosphate, an event that is modulated by G protein signaling pathways and provides a link between phosphoinositide metabolism and G protein signal transduction. The gene encoding GDE1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
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