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GDE1 Antikörper (AA 231-331) (Biotin)

GDE1 Reaktivität: Maus WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1394809
  • Target Alle GDE1 Antikörper anzeigen
    GDE1 (Glycerophosphodiester Phosphodiesterase 1 (GDE1))
    Bindungsspezifität
    • 14
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 231-331
    Reaktivität
    • 26
    • 20
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 33
    • 7
    • 1
    Kaninchen
    Klonalität
    • 37
    • 4
    Polyklonal
    Konjugat
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GDE1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 39
    • 21
    • 13
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MIR16/GDE1
    Isotyp
    IgG
    Top Product
    Discover our top product GDE1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    GDE1 (Glycerophosphodiester Phosphodiesterase 1 (GDE1))
    Andere Bezeichnung
    MIR16/GDE1 (GDE1 Produkte)
    Synonyme
    zgc:56068 antikoerper, zgc:77135 antikoerper, 363E6.2 antikoerper, MIR16 antikoerper, 1200003M13Rik antikoerper, Mir16 antikoerper, RGS16 antikoerper, glycerophosphodiester phosphodiesterase 1 antikoerper, glycerophosphodiester phosphodiesterase 1 L homeolog antikoerper, gde1 antikoerper, gde1.L antikoerper, GDE1 antikoerper, Gde1 antikoerper
    Hintergrund

    Synonyms: EC 3.1.4.44, GDE1, Glycerophosphodiester phosphodiesterase 1, Membrane interacting protein of RGS16, RGS16 interacting membrane protein, GDE1_HUMAN.

    Background: GDE1 is a 331 amino acid multi-pass membrane protein that localizes to both the membrane and the cytoplasm and contains one GDPD domain. Expressed in a wide variety of tissues, GDE1 uses magnesium as a cofactor to catalyze the conversion of 1-(sn-glycero-3-phospho)-1D-myo-inositol to myo-inositol and sn-glycerol 3-phosphate, an event that is modulated by G protein signaling pathways and provides a link between phosphoinositide metabolism and G protein signal transduction. The gene encoding GDE1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

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