UNCX Antikörper (AA 145-150) (AbBy Fluor® 647)

Produktnummer ABIN1394832

Produktdetails anti-UNCX Antikörper (AbBy Fluor® 647)

Target: UNCX (UNC Homeobox (UNCX))

Bindungsspezifität: AA 145-150

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNCX Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UNCX

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu UNCX

Target: UNCX (UNC Homeobox (UNCX))

Andere Bezeichnung: UNCX (UNCX Produkte)

Synonyme: UNCX4.1 antikoerper, Chx4 antikoerper, Uncx4.1 antikoerper, PHD1 antikoerper, uncx-4.1 antikoerper, uncx4.1 antikoerper, uncx4.1.2 antikoerper, UNC homeobox antikoerper, homeobox protein unc-4 homolog antikoerper, UNC homeobox L homeolog antikoerper, UNCX antikoerper, LOC100447436 antikoerper, LOC100447805 antikoerper, uncx antikoerper, Uncx antikoerper, uncx.L antikoerper

Hintergrund:

Synonyms: Homeobox protein unc-4 homolog, Homeobox protein Uncx4.1, tcag7.1272, UNC homeobox, Unc4.1 homeobox, UNC4_HUMAN, Uncx, UNCX4.1.

Background: Members of the paired homeobox family play a role in regulating cell development and pattern formation during embryonic stages. UNCX (UNC homeobox), also known as UNCX4.1, is a 531 amino acid nuclear transcription factor involved in neurogenesis and somitogenesis. Containing one homeobox DNA-binding domain, UNCX belongs to the paired homeobox family and UNC4 subfamily. UNCX assists in the formation of connections between hypothalamic neurons and the pituitary, which is necessary for central neurons to deliver hormones into peripheral blood. UNCX also plays a role in maintaining differentiation of the axial skeleton and acts upstream of Pax-9. The gene encoding UNCX maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5 % of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.