GABRB1 Antikörper (pSer434) (AbBy Fluor® 488)
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- Target Alle GABRB1 Antikörper anzeigen
- GABRB1 (gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1))
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Bindungsspezifität
- pSer434
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GABRB1 Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human GARB1 around the phosphorylation site of Ser434
- Isotyp
- IgG
- Top Product
- Discover our top product GABRB1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- GABRB1 (gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1))
- Andere Bezeichnung
- GARB1 (GABRB1 Produkte)
- Synonyme
- AW061132 antikoerper, B230208N19Rik antikoerper, Gabrb-1 antikoerper, GARB1 antikoerper, si:dkey-20i10.4 antikoerper, gamma-aminobutyric acid type A receptor beta1 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 antikoerper, gamma-aminobutyric acid type A receptor beta 1 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, beta 1 antikoerper, GABRB1 antikoerper, Gabrb1 antikoerper, gabrb1 antikoerper
- Hintergrund
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Synonyms: GABA A Receptor beta 1 phospho S434; GARB1 Ser 434; GABAA receptor subunit beta-1; GABA-A receptor, beta-1 polypeptide; Gabrb-1; Gamma Aminobutyric Acid A Receptor Beta 1; Gamma Aminobutyric Acid Receptor , beta-1; Gamma-aminobutyric acid GABA A receptor, subunit beta 1; Gamma-aminobutyric acid receptor subunit beta-1; GARB1; GABRA1; AW061132; B230208N19Rik; GABAA receptor beta 1; GABAA receptor subunit beta-1; GABA-A receptor, beta-1 polypeptide; Gabrb-1; GABRB1; Gamma aminobutyric acid GABA A receptor beta 1; Gamma Aminobutyric Acid A Receptor Beta 1; Gamma Aminobutyric Acid Receptor , beta-1; Gamma-aminobutyric acid GABA A receptor, subunit beta 1; Gamma-aminobutyric acid receptor subunit beta-1; GARB1; GBRB1_HUMAN.
Background: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (g-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R alpha 1-6, GABAA R beta 1-3, GABAA R©1-3, GABAA R∂, GABAA R gamma, GABAA R delta 1 and GABAA R delta 2. The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2 and -3). The GABA transporters function to terminate GABA action.
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