GABARAP Antikörper (AA 11-117) (AbBy Fluor® 350)

Produktnummer ABIN1395051

Produktdetails anti-GABARAP Antikörper (AbBy Fluor® 350)

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Bindungsspezifität: AA 11-117

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABARAP Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GABARAP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GABARAP

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Andere Bezeichnung: GABARAP (GABARAP Produkte)

Synonyme: GABARAP antikoerper, ATG8A antikoerper, GABARAP-a antikoerper, MM46 antikoerper, gabarap antikoerper, mg:bb02b03 antikoerper, GABA type A receptor-associated protein antikoerper, gamma-aminobutyric acid receptor-associated protein antikoerper, GABA(A) receptor-associated protein a antikoerper, gamma-aminobutyric acid receptor associated protein antikoerper, GABARAP antikoerper, LOC5568843 antikoerper, Gabarap antikoerper, gabarapa antikoerper

Hintergrund:

Synonyms: ATG8A, FLC 3B, FLC3B, FLJ25768, GABAA receptor associated protein, GABAA receptor-associated protein, GABARAP a, GABARAP, Gamma aminobutyric acid receptor associated protein, Gamma-aminobutyric acid receptor-associated protein, GBRAP_HUMAN, MGC120154, MGC120155, MM 46, MM46.

Background: In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA ) and metabotropic (GABAB ) receptors as well as a third class of receptors called GABAC. In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton. The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex.

Pathways: Autophagie