DLGAP1 Antikörper (AA 241-360) (Biotin)

Produktnummer ABIN1395385

Produktdetails anti-DLGAP1 Antikörper (Biotin)

Target: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Bindungsspezifität: AA 241-360

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLGAP1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SAPAP1/DLGAP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DLGAP1

Target: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Andere Bezeichnung: SAPAP1/DLGAP1 (DLGAP1 Produkte)

Synonyme: DKFZp469D0713 antikoerper, gkap antikoerper, sapap1 antikoerper, DAP-1 antikoerper, DAP-1-ALPHA antikoerper, DAP-1-BETA antikoerper, GKAP antikoerper, SAPAP1 antikoerper, hGKAP antikoerper, 4933422O14Rik antikoerper, 9630002F18 antikoerper, AI845682 antikoerper, AI848168 antikoerper, BB075781 antikoerper, D17Bwg0511e antikoerper, GKAP/SAPAP antikoerper, GKPA/SAPAP antikoerper, Gkap antikoerper, Sapap1 antikoerper, mKIAA4162 antikoerper, DLG associated protein 1 antikoerper, discs, large (Drosophila) homolog-associated protein 1 antikoerper, disks large-associated protein 1 antikoerper, discs, large homolog-associated protein 1 antikoerper, discs, large (Drosophila) homolog-associated protein 1b antikoerper, DLGAP1 antikoerper, LOC100408093 antikoerper, LOC100548434 antikoerper, dlgap1 antikoerper, Dlgap1 antikoerper, dlgap1b antikoerper

Hintergrund:

Synonyms: PSD95 binding protein 1, DAP 1 ALPHA, DAP 1, DAP 1 BETA, DAP-1, DAP-1-ALPHA, DAP-1-BETA, DAP1, Discs large Drosophila homolog associated protein 1, Discs large homolog associated protein 1, Disks large associated protein 1, Disks large associated protein 1, alpha isoform, included, Disks large associated protein 1, beta isoform, included, Disks large-associated protein 1, DLGAP 1, Dlgap1, DLGP1_HUMAN, GKAP, GKAP/SAPAP, GKPA/SAPAP, Guanylate kinase associated protein, Guanylate kinase-associated protein, hGKAP, KIAA4162, MGC88156, mKIAA4162, PSD 95/SAP90 binding protein 1, PSD-95/SAP90-binding protein 1, SAP90/PSD 95 associated protein 1, SAP90/PSD-95-associated protein 1, SAPAP 1, SAPAP1.

Background: Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membrane-associated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-a, DAP-1-b, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP, through the guanylate kinase domain. GKAP is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. GKAP is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.