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THO Complex 2 Antikörper (AA 101-200) (AbBy Fluor® 555)

THOC2 Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 555
Produktnummer ABIN1396048
  • Target Alle THO Complex 2 (THOC2) Antikörper anzeigen
    THO Complex 2 (THOC2)
    Bindungsspezifität
    • 14
    • 2
    • 2
    AA 101-200
    Reaktivität
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 19
    Kaninchen
    Klonalität
    • 19
    Polyklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser THO Complex 2 Antikörper ist konjugiert mit AbBy Fluor® 555
    Applikation
    • 18
    • 12
    • 12
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human THOC2
    Isotyp
    IgG
    Top Product
    Discover our top product THOC2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    THO Complex 2 (THOC2)
    Andere Bezeichnung
    Thoc2 (THOC2 Produkte)
    Synonyme
    RGD1561623 antikoerper, THO antikoerper, Tho2 antikoerper, fb73e08 antikoerper, fd21d11 antikoerper, wu:fb73e08 antikoerper, wu:fd21d11 antikoerper, si:bz1o18.2 antikoerper, CXorf3 antikoerper, THO2 antikoerper, dJ506G2.1 antikoerper, hTREX120 antikoerper, 6330441O12Rik antikoerper, D130005M13Rik antikoerper, Gm1139 antikoerper, Gm1793 antikoerper, THO complex 2 antikoerper, Thoc2 antikoerper, THOC2 antikoerper, thoc2 antikoerper
    Hintergrund

    Synonyms: THO2, CXorf3, hTREX120, dJ506G2.1, THO complex subunit 2, THOC2

    Background: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains. Required for NXF1 localization to the nuclear rim.

    Gen-ID
    57187
    UniProt
    Q8NI27
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