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SLC51B Antikörper (AbBy Fluor® 488)

OSTBETA Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal AbBy Fluor® 488
Produktnummer ABIN1396083
  • Target Alle SLC51B (OSTBETA) Antikörper anzeigen
    SLC51B (OSTBETA) (Organic Solute Transporter beta (OSTBETA))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 23
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SLC51B Antikörper ist konjugiert mit AbBy Fluor® 488
    Applikation
    • 18
    • 7
    • 3
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human OST-beta
    Isotyp
    IgG
    Top Product
    Discover our top product OSTBETA Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    SLC51B (OSTBETA) (Organic Solute Transporter beta (OSTBETA))
    Andere Bezeichnung
    Ost-beta (OSTBETA Produkte)
    Synonyme
    Ostb antikoerper, Ostbeta antikoerper, RGD1565748 antikoerper, OSTB antikoerper, OSTBETA antikoerper, solute carrier family 51, beta subunit antikoerper, solute carrier family 51 beta subunit antikoerper, Slc51b antikoerper, SLC51B antikoerper
    Hintergrund

    Synonyms: organic solute transporter beta Ostbeta, Organic solute transporter subunit beta, Ostbeta, Ost beta, OST-beta, OSTB, OSTB_HUMAN.

    Background: The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine, liver, testis, kidney and adrenal gland. OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor). This genetic regulation suggests that in response to changes in intracellular bile acid levels, bile acids adjust the rate of their own efflux from enterocytes. OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane. Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus. Though widely expressed, OST Beta is present at highest levels in ileum.

    Gen-ID
    123264
    Pathways
    Regulation of Carbohydrate Metabolic Process
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