HIV-1 p17/p24/p55 (AA 231-330) Antikörper (Biotin)

Produktnummer ABIN1397094

Produktdetails

Target: HIV-1 p17/p24/p55

Bindungsspezifität: AA 231-330

Reaktivität: Human Immunodeficiency Virus (HIV), Virus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA

Kreuzreaktivität: Virus

Kreuzreaktivität (Details): HIV1

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from HIV1 Pr55Gag

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Antigendetails

Target: HIV-1 p17/p24/p55

Andere Bezeichnung: HIV1 p55+p24+p17

Substanzklasse: Viral Protein

Hintergrund:

Synonyms: HIV p55+Capsid protein p24, HIV1 p55 + p24 + p17, CA antibody Capsid protein p24, Gag, Gag polyprotein, HIV1 matrix protein p17, HIV1 Pr55Gag, Human immunodeficiency virus 1 p17, Human immunodeficiency virus 1 p55, Human immunodeficiency virus type 1 p24, MA antibody Matrix protein, Matrix protein p17, Pr55, Pr55Gag, POL_HV1H2.

Background: HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. p55 is digested by HIV1 protease into intermediate products p41 and p15. p41 is further digested into matrix protein p17 and capsid protein p24. Likewise, p15 is further digested into nucleocapsid protein p7 and to p6 and p1.